0000-0002-6946-1097
2021
Efficacy and safety of nitazoxanide plus atazanavir/ritonavir for the treatment of moderate to severe COVID-19 (NACOVID): A structured summary of a study protocol for a randomised controlled trial
A Olagunju, A Fowotade, A Olagunoye, TO Ojo, BO Adefuye, AF Fagbamigbe, AO Adebiyi, OI Olagunju, OT Ladipo, A Akinloye, BA Adeagbo, A Onayade, OO Bolaji, C Happi,
S Rannard & A Owen
Trials 2021, 22, 3
Scalable nanoprecipitation of niclosamide and in vivo demonstration of long-acting delivery after intramuscular injection
JJ Hobson, AC Savage, AB Dwyer, C Unsworth, J Massam, U Arshad, H Pertinez, H Box,
L Tatham, RKR Rajoli, M Neary, J Sharp,
A Valentijn, C David, P Curley, NJ Liptrott,
TO McDonald, A Owen, SP Rannard
Nanoscale, 2021, 13, 6410 - 6416
(also ChemRxiv 2021; DOI: https://doi.org/10.26434/chemrxiv.13587035.v1)
Development of a highly sensitive bioanalytical assay for the quantification of favipiravir
P Curley, M Neary,U Arshad, L Tatham, H Pertinez, H Box, RKR Rajoli, A Valentijn, J Sharp,
SP Rannard, A Owen
BioRxiv 2021; DOI: https://doi.org/10.1101/2021.02.03.429628
Redispersible Nanosuspensions as a Plausible Oral Delivery System for Curcumin
NM Elbaz, LM Tatham, A Owen, S Rannard, TO McDonald
Food Hydrocolloids., 2021, 121, 107005
Optimisation and validation of a sensitive bioanalytical method for niclosamide
U Arshad, H Pertinez, H Box, L Tatham, R Rajoli, M Neary, J Sharp, A Valentijn, J Hobson, C Unsworth, A Dwyer, A Savage, TO McDonald, S Rannard, P Curley, A Owen,
BioRxiv 2021; DOI: https://doi.org/10.1101/2021.01.13.426426
Dose prediction for repurposing nitazoxanide in
SARS-CoV-2 treatment or chemoprophylaxis
RKR Rajoli, H Pertinez, U Arshad, H Box, L Tatham, P Curley, M Neary, J Sharp, NJ Liptrott,
A Valentijn, C David, SP Rannard, G Aljayyoussi,
SH Pennington, A Hill, M Boffito, SA Ward, SH Khoo, PG Bray, PM O'Neill, WD Hong,
Br. J. Clin. Pharmacol., 2021, 87, 2078–2088
Quantification of branching within high molecular weight polymers with polyester backbones formed by transfer-dominated branching radical telomerisation (TBRT)
S Cassin, S Flynn, P Chambon & SP Rannard
RSC Advances, 2021, 11, 24374 - 24380
Quantitation of tizoxanide in multiple matrices to support cell culture, animal and human research
M Neary, U Arshad, L Tatham, H Pertinez, H Box, RK Rajoli, A Valentijn, J Sharp, SP Rannard, GA Biagini, P Curley, A Owen
BioRxiv 2021; DOI:10.1101/2021.05.27.445500
Evaluation of intranasal nafamostat or camostat for SARS-CoV-2 chemoprophylaxis in Syrian golden hamsters
M Neary, H Box, J Sharp, L Tatham, P Curley, J Herriott, E Kijak, U Arshad, JJ Hobson, RKR Rajoli, H Pertinez, A Valentijn, K Dhaliwal, F McCaughan, SP Rannard, A Kipar, JP Stewart, A Owen
BioRxiv 2021; DOI:10.1101/2021.07.08.451654
Impact of Long-Acting Therapies on the Global HIV Epidemic
N C. Chandiwana, C. M. Serenata, A. Owen, S. Rannard; C. Perez Casas, C. Scott, A. HILL, P. Clayden, C Flexner
AIDS, 2021, 35 (Supplement 2), S137-S143
Impact of multi-vinyl taxogen dimensions on high molecular weight soluble polymer synthesis using Transfer-dominated Branching Radical Telomerisation
O.B. Penrhyn-Lowe, S Flynn, S. R. Cassin, S Mckeating, S Lomas, S Wright, P Chambon and
S. P. Rannard
Polymer Chem., 2021, 12, 6472 - 6483
Evaluating the impact of systematic hydrophobic modification of model drugs on the control, stability and loading of lipid-based nanoparticles
C Hogarth, K Arnold, A McLauchlin, S Rannard,
M Siccardi, TO McDonald
J. Mater. Chem. B, 2021, 9, 9874-9884
Randomised controlled trial of intravenous nafamostat mesylate in COVID pneumonitis: phase 1b/2a experimental study to investigate safety, pharmacokinetics and pharmacodynamics
T. M. Quinn, E. E. Gaughan, A. Bruce, J. Antonelli, R. O'Connor, F. Li, S. McNamara, O. Koch, C. MacIntosh, D. Dockrell, T. Walsh, K. G. Blyth, C. Church, J. Schwarze, C. Boz, A. Valanciute, M. Burgess, P. Emanuel, B. Mills, G. Rinaldi, G. Hardisty, R. Mills, E. Findlay, S. Jabbal, A. Duncan, S. Plant, A. D. L. Marshall, I. Young, K. Russell, E. Scholefield, A. F. Nimmo, I. B. Nazarov, G. C. Churchill, J. S. O. McCullagh, K. H. Ebrahimi, C. Ferrett, K. Templeton, S. Rannard, A. Owen, A. Moore, K. Finlayson, M. Shankar-Hari, J. Norrie, R. A. Parker, A. R. Akram, D. C. Anthony, J. W. Dear, N. Hirani, K. Dhaliwal
medRxiv 2021 DOI: 10.1101/2021.10.06.21264648
2020
Controlled Synthesis of Calcium Carbonate Nanoparticles and Stimuli-Responsive Multi-Layered Nanocapsules for Oral Drug Delivery
N Elbaz, A Owen, S Rannard, T McDonald
Int. J. Pharmaceutics. 2020, 574, 118866
Architectural control of polystyrene physical properties using branched anionic polymerisation initiated at ambient temperature
T Alhilfi, P Chambon, S. P. Rannard
J. Polym. Sci., Part A: Poly. Chem., 2020, 58, 1426-1438
Safety assessment of a new nanoemulsion-based drug delivery system reveals unexpected, drug-free, anticoagulant activity
JJ Hobson, SP Rannard, A Owen, NJ Liptrott
Nanomedicine 2020, 15, 1361-1373
Chasing COVID-19 chemotherapeutics without putting the cart before the horse
S Rannard, T McDonald, A Owen
British Journal of Clinical Pharmacology 2020, accepted DOI: 10.22541/au.159413561.14757083
Optimization of the Synthetic Parameters of Lipid Polymer Hybrid Nanoparticles Dual Loaded with Darunavir and Ritonavir for the Treatment of HIV
H Elkateb,LM Tatham, H Cauldbeck,
E Niezabitowska, A Owen, S Rannard T McDonald
Int. J. Pharmaceutics, 2020,588, 119794
Designing single trigger/dual-response release and degradation into amine-functional hyperbranched-polydendron nanoprecipitates
HE Rogers, P Chambon, S Flynn, FY Hern, A Owen, SP Rannard
Nanoscale Adv, 2020, 2, 5468 - 5477
Critical considerations for targeting metastatic colorectal cancer with nanotechnology
U Arshad, C Goldring, P Sutton, M Ashford, K Treacher, S Rannard, A Owen
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 2020, 12(2), e1588
Prioritisation of Anti-SARS-Cov-2 Drug Repurposing Opportunities Based on Plasma and Target Site Concentrations Derived from their Established Human Pharmacokinetics
U Arshad, H Pertinez, H Box, L Tatham, RKR Rajoli, P Curley, M Neary, J Sharp, NJ Liptrott, A Valentijn,
C David, SP Rannard, P O'Neill, G Aljayyoussi,
S Pennington, SA Ward, DJ Back, SH Khoo, PG Bray, G Biagini, A Owen
Clin. Pharmacol. Ther., 2020, 108, 775-790
Mucus-responsive functionalized emulsions: Design, synthesis and study of novel branched polymers as functional emulsifiers
SE. Edwards, S Flynn, JJ. Hobson, P Chambon, H Cauldbeck S P Rannard
RSC Adv., 2020, 10, 30463-30475
Insights into the Internal Structures of Nanogels Using a Versatile Asymmetric-Flow Field-Flow Fractionation Method
E Niezabitowska, AR Town, B Sabagh, MD
Morales Moctezuma, VR Kearns, SG. Spain, SP Rannard TO McDonald
Nanoscale Adv., 2020, doi.org/10.1039/D0NA00314J
Using pyrene to probe the effects of poloxamer stabilisers on internal lipid microenvironments in solid lipid nanoparticles.
JM Taylor, K Scale, S Arrowsmith, A Sharp,
S Flynn, S Rannard, TO McDonald
Nanoscale Adv., 2020,2, 5572-5577
Hyperbranched polymers with step-growth chemistries from transfer-dominated branching radical telomerisation (TBRT) of divinyl monomers.
SR Cassin, P Chambon, SP Rannard
Polymer Chem., 2020, 11, 7637 - 7649
2019
Semi-solid prodrug nanoparticles for long-acting delivery of water-soluble antiretroviral drugs within combination HIV therapies
J J Hobson, A Al-khouja, P Curley, D Meyers, C Flexner, M Siccardi, A Owen, C Freel Meyers, S P Rannard
Nature Communications 2019, 10, 1413
On the issue of transparency and reproducibility in nanomedicine
H. S. Leong et al
Nature Nanotechnology 2019, 14, 629
Long-Acting Injectable Statins—Is It Time for a Paradigm Shift?
L M Tatham, N J Liptrott, S P Rannard, A Owen
Molecules 2019, 24(15), 2685
Expanding the monomer scope of linear and branched vinyl polymerisations via copper-catalysed reversible-deactivation radical polymerisation of hydrophobic methacrylates using anhydrous alcohol solvents.
S Flynn, A B Dwyer, P Chambon, S Rannard
Polymer Chem. 2019, 10, 5103 - 5115
Anhydrous nanoprecipitation for the preparation of nanodispersions of tenofovir disoproxil fumarate in oils as candidate long-acting injectable depot formulations
J J Hobson, P Curley, A C Savage, A Al-khouja, M Siccardi, C Flexner, C Freel Meyers, A Owen, S P Rannard
Nanoscale Advances, 2019, 1(11), 4301-4307
Extending Dendrimer Chemistry to Unique Macromolecular Architectures
A B Dwyer and S P Rannard
RSC Monographs in Supramolecular Chemistry, Dendrimer Chemistry, 2019, accepted
