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0000-0002-6946-1097
2015
The application of nanotechnology to drug delivery in Medicine.
T. O. McDonald, M. Siccardi, D. Moss, N. Liptrott,
M. Giardiello, S. Rannard & A. Owen
Nanoengineering: Global Approaches to Health and Safety Issues. P. Dolez (Ed), Elsevier Health Sciences, Toronto, 2015, Chapter 2.2, 173-223
ISBN: 978-0-444-62747-6
Synthesis and in vivo magnetic resonance imaging evaluation of biocompatible branched copolymer nanocontrast agents
A. W. Jackson , P. Chandrasekharan, J. Shi,
S. P. Rannard, Q. Liu, C. T. Yang & T. He
Int J Nanomedicine, 2015, 10, 5895—5907
Considerations for clinically-relevant nanomedicine therapies for chronic diseases
A. Owen & S. P. Rannard
Nanomedicine (Lond.), 2015 10, 3103–3107
Augmented inhibition of CYP3A4 in human primary hepatocytes by ritonavir solid drug nanoparticles
P, Martin, M. Giardiello, T. McDonald, D. Smith,
M. Siccardi, S. Rannard & A Owen,
Mol. Pharmaceutics 2015,12, 3556–3568
Synthesis, nanoprecipitation and pH sensitivity of amphiphilic linear-dendritic hybrid polymers and hyperbranched-polydendrons containing tertiary amine functional dendrons
H. E. Rogers, P. Chambon, S. E. R. Auty, F. Y. Hern, A. Owen & S. P. Rannard
Soft Matter, 2015, 11, 7005-7015
Exploring the homogeneous controlled radical polymerisation of hydrophobic monomers in anti-solvents for their polymers: RAFT and ATRP of various alkyl methacrylates in anhydrous methanol to high conversion and low dispersity.
A. B. Dwyer, P. Chambon, A. Town, F. L. Hatton,
J. Ford & S. P. Rannard.
Polym.Chem. Sci., 2015, 6, 7286 - 7296
Flow cytometric analysis of the physical and protein-binding characteristics of solid drug nanoparticle suspensions
N. J. Liptrott , M. Giardiello , J. W Hunter , L. Tatham , L. R Tidbury , M. Siccardi, S. Rannard & A. Owen
Nanomedicine (London) 2015, 10, 1407-1421
Nanoformulation strategies for the enhanced oral bioavailability of antiretroviral therapeutics.
L. Tatham, S. P. Rannard & A. Owen
Ther. Deliv., 2015, 6, 469-490
Multiple and Co-Nanoprecipitation Studies of Branched Hydrophobic Copolymers and A–B Amphiphilic Block Copolymers, Allowing Rapid Formation of Sterically Stabilized Nanoparticles in Aqueous Media.
J. Ford, P. Chambon, J. North, F. L. Hatton,
M. Giardiello, A. Owen & S P. Rannard
Macromolecules, 2015, 48, 1883-1899
Physiologically Based Pharmacokinetic Modelling to Inform Development of Intra-muscular Long-Acting Nanoformulations for HIV
R. K. R. Rajoli, D. J. Back, S. Rannard,
C. L. Freel Meyers, C. Flexner, A. Owen & M. Siccardi
Clin. Pharmacokinet., 2015, 54, 639-650.
One-pot’ sequential deprotection/functionalisation of linear-dendritic hybrid polymers using a xanthate mediated thiol/Michael addition.
S. E. R. Auty, O. C. J. Andrén, F.Y. Hern, M. Malkoch & S. P. Rannard
Polym. Chem., 2015, 6, 573 - 582
Hyperbranched Polydendrons: a new nanomaterials platform with tuneable permeation through model gut epithelium.
F. L. Hatton, L. M. Tatham, L. R. Tidbury, P. Chambon, T. He, A. Owen & S. Rannard
Chem. Sci., 2015, 6(1), 326 - 334
2014
2014
Partial mitigation of gold nanoparticle-interactions with human lymphocytes by surface functionalization with a ‘mixed-matrix’
N. J. Liptrott, E. Kendall, D. J. Nieves, J. Farrell, S. Rannard, D. G Fernig & A. Owen
Nanomedicine (London) 2014, 9, 2467-2479
The application of nanotechnology in
medicine: treatment and diagnostics
A. Owen, C. Dufès, D. Moscatelli, E. Mayes, J. F. Lovell, K. V. Katti, K. Sokolov, M. Mazza, O. Fontaine, S. Rannard & V. Stone
Nanomedicine, 2014, 9(9), 1291–1294
The First Peripherally Masked Thiol Dendrimers: A Facile and Highly Efficient Functionalization Strategy of Polyester Dendrimers via One-Pot Xanthate Deprotection/Thiol-Acrylate Michael Addition Reactions.
S. E. R. Auty, O. Andrén, M. Malkoch & S. P. Rannard
Chem. Commun. 2014, 50, 6574 - 6577
Is methanol really a bad solvent for poly(n-butyl methacrylate)? Low dispersity and high molecular weight polymers of n-butyl methacrylate synthesised via ATRP in anhydrous methanol.
A. B. Dwyer, P. Chambon, A. Town, T. He, A. Owen & S. P. Rannard
Polym.Chem. 2014, 5 (11), 3608 - 3616
Hyperbranched Polydendrons: a new controlled macromolecular architecture with self-assembly in water and organic solvents.
F. L. Hatton, P. Chambon, T. O. McDonald,
A. Owen & S. P. Rannard
Chem. Sci., 2014, 5(5), 1844 - 1853
Antiretroviral Solid Drug Nanoparticles with Enhanced Oral Bioavailability: Production, Characterisation and In Vitro-In Vivo Correlation.
T. O. McDonald, M. Giardiello, P. Martin, M. Siccardi, N. J. Liptrott, D. Smith, P. Roberts, P. Curley, A. Schipani, S. H. Khoo, J. Long, A. J. Foster, S. P. Rannard & A. Owen
Adv. Healthcare Mater., 2014, 3, 400–411
2013
2013
High-throughput nanoprecipitation of the organic antimicrobial triclosan and enhancement of activity against Escherichia coli
T. O. McDonald, L. M. Tatham, F. Y. Southworth, M. Giardiello, P. Martin, N. J. Liptrott, A. Owen
& S. P. Rannard
J. Mater. Chem. B, 2013, 1, 4455-4465
Reactions of hydrophobic organic nanoparticle mixtures in water: Nanoparticle-on-nanoparticle oxidative dye bleaching
M. Giardiello,T. O. McDonald, J-S. Lee,
A. D. Roberts, A. Owen & S. P. Rannard
Green Chem., 2013, 15(6), 1590-1599
Mediation of in vitro cytochrome P450 activity by common pharmaceutical excipients
P. Martin, M. Giardiello, T. O. McDonald,
S. P. Rannard & A. Owen
Mol. Pharmaceutics 2013, 107, 2739–2748
Research Spotlight: Nanomedicines for HIV therapy
M. Siccardi, P. Martin, T. O. McDonald, N. J. Liptrott, M. Giardiello, S. Rannard & A. Owen
Therapeutic Delivery 2013, 4(2), 153-156
Use of a physiologically-based pharmacokinetic model to simulate artemether dose adjustment for overcoming the drug-drug interaction with efavirenz
M.Siccardi, A. Olagunju, K. Seden, F. Ebrahimjee,
S. Rannard, D. Back & A. Owen
In Silico Pharmacology 2013, 1, 4
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